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A fork in the road: Where homologous recombination and stalled replication fork protection part ways
In response to replication hindrances, DNA replication forks frequently stall and are remodelled into a four-way junction. In such a structure the annealed nascent strand is thought to resemble a DNA double-strand break and remodelled forks are vulnerable to nuclease attack by MRE11 and DNA2. Protei...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082280/ https://www.ncbi.nlm.nih.gov/pubmed/32653304 http://dx.doi.org/10.1016/j.semcdb.2020.07.004 |