C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera

Systemic complement activation drives a plethora of pathological conditions, but its role in snake envenoming remains obscure. Here, we explored complement’s contribution to the physiopathogenesis of Naja annulifera envenomation. We found that N. annulifera venom promoted the generation of C3a, C4a,...

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Detalles Bibliográficos
Autores principales: Silva de França, Felipe, Villas-Boas, Isadora Maria, Cogliati, Bruno, Woodruff, Trent M., Reis, Edimara da Silva, Lambris, John D., Tambourgi, Denise V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082402/
https://www.ncbi.nlm.nih.gov/pubmed/33936074
http://dx.doi.org/10.3389/fimmu.2021.652242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082402/
https://www.ncbi.nlm.nih.gov/pubmed/33936074
http://dx.doi.org/10.3389/fimmu.2021.652242

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