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Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes

Combinatorial and modular methods to synthesize small molecule modulators of protein activity have proven to be powerful tools in the development of new drug-like molecules. Over the past decade, these methodologies have been adapted toward utilization in the development of activity- and affinity-ba...

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Detalles Bibliográficos
Autores principales: van der Zouwen, Antonie J., Witte, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082414/
https://www.ncbi.nlm.nih.gov/pubmed/33937194
http://dx.doi.org/10.3389/fchem.2021.644811