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M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway

Platelet derived growth factor receptor β positive (PDGFRβ(+)) pericytes form fibrotic scar, which prevents axonal regeneration after spinal cord injury (SCI). However, the mechanism by which PDGFRβ(+) pericytes migrate to the injury core is unclear. Here, we investigated the effect and mechanism of...

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Detalles Bibliográficos
Autores principales: Li, Ziyu, Zheng, Meige, Yu, Shuisheng, Yao, Fei, Luo, Yang, Liu, Yanchang, Tian, Dasheng, Cheng, Li, Jing, Juehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082415/
https://www.ncbi.nlm.nih.gov/pubmed/33935795
http://dx.doi.org/10.3389/fphar.2021.670813