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Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 Diabetes

Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes derived from T1D-associated antigens have been ident...

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Detalles Bibliográficos
Autores principales: Mishto, Michele, Mansurkhodzhaev, Artem, Rodriguez-Calvo, Teresa, Liepe, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082463/
https://www.ncbi.nlm.nih.gov/pubmed/33936085
http://dx.doi.org/10.3389/fimmu.2021.656451