An Integrated Genomic, Proteomic, and Immunopeptidomic Approach to Discover Treatment-Induced Neoantigens

All nucleated mammalian cells express major histocompatibility complex (MHC) proteins that present peptides on cell surfaces for immune surveillance. These MHC-presented peptides (pMHC) are necessary for directing T-cell responses against cells harboring non-self antigens derived from pathogens or f...

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Detalles Bibliográficos
Autores principales: Olsson, Niclas, Heberling, Marlene L., Zhang, Lichao, Jhunjhunwala, Suchit, Phung, Qui T., Lin, Sarah, Anania, Veronica G., Lill, Jennie R., Elias, Joshua E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082494/
https://www.ncbi.nlm.nih.gov/pubmed/33936100
http://dx.doi.org/10.3389/fimmu.2021.662443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082494/
https://www.ncbi.nlm.nih.gov/pubmed/33936100
http://dx.doi.org/10.3389/fimmu.2021.662443

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