Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency

Long-chain fatty acid oxidation is frequently impaired in primary and systemic metabolic diseases affecting the heart; thus, therapeutically increasing reliance on normally minor energetic substrates, such as ketones and medium-chain fatty acids, could benefit cardiac health. However, the molecular...

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Detalles Bibliográficos
Autores principales: Pereyra, Andrea S., Harris, Kate L., Soepriatna, Arvin H., Waterbury, Quin A., Bharathi, Sivakama S., Zhang, Yuxun, Fisher-Wellman, Kelsey H., Goergen, Craig J., Goetzman, Eric S., Ellis, Jessica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082564/
https://www.ncbi.nlm.nih.gov/pubmed/33757734
http://dx.doi.org/10.1016/j.jlr.2021.100069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082564/
https://www.ncbi.nlm.nih.gov/pubmed/33757734
http://dx.doi.org/10.1016/j.jlr.2021.100069

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