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IL‐17 drives salivary gland dysfunction via inhibiting TRPC1‐mediated calcium movement in Sjögren’s syndrome

OBJECTIVES: This study aims to determine a role of interleukin‐17A (IL‐17) in salivary gland (SG) dysfunction and therapeutic effects of targeting IL‐17 in SG for treating autoimmune sialadenitis in primary Sjögren’s syndrome (pSS). METHODS: Salivary IL‐17 levels and IL‐17‐secreting cells in labial...

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Detalles Bibliográficos
Autores principales: Xiao, Fan, Du, Wenhan, Zhu, Xiaoxia, Tang, Yuan, Liu, Lixiong, Huang, Enyu, Deng, Chong, Luo, Cainan, Han, Man, Chen, Ping, Ding, Liping, Hong, Xiaoping, Wu, Lijun, Jiang, Quan, Zou, Hejian, Liu, Dongzhou, Lu, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082715/
https://www.ncbi.nlm.nih.gov/pubmed/33968407
http://dx.doi.org/10.1002/cti2.1277