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Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment

BACKGROUND: Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution are manifestations of this clonal complexity. The analysis of the mechanisms...

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Detalles Bibliográficos
Autores principales: Fernandez Do Porto, Darío A., Monteserin, Johana, Campos, Josefina, Sosa, Ezequiel J., Matteo, Mario, Serral, Federico, Yokobori, Noemí, Benevento, Andrés Fernández, Poklepovich, Tomás, Pardo, Agustín, Wainmayer, Ingrid, Simboli, Norberto, Castello, Florencia, Paul, Roxana, Martí, Marcelo, López, Beatriz, Turjanski, Adrián, Ritacco, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082761/
https://www.ncbi.nlm.nih.gov/pubmed/33926375
http://dx.doi.org/10.1186/s12879-021-06069-9