The impact of cell type and context-dependent regulatory variants on human immune traits

BACKGROUND: The vast majority of trait-associated variants identified using genome-wide association studies (GWAS) are noncoding, and therefore assumed to impact gene regulation. However, the majority of trait-associated loci are unexplained by regulatory quantitative trait loci (QTLs). RESULTS: We...

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Detalles Bibliográficos
Autores principales: Mu, Zepeng, Wei, Wei, Fair, Benjamin, Miao, Jinlin, Zhu, Ping, Li, Yang I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082814/
https://www.ncbi.nlm.nih.gov/pubmed/33926512
http://dx.doi.org/10.1186/s13059-021-02334-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082814/
https://www.ncbi.nlm.nih.gov/pubmed/33926512
http://dx.doi.org/10.1186/s13059-021-02334-x

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