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The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance

BACKGROUND: Sphingomyelin (SM) is an essential component of biological lipid rafts, and it plays an indispensable role in maintaining plasma membrane stability and in mediating signal transduction. The ultimate biosynthesis of SM is catalyzed by two sphingomyelin synthases (SMSs) namely SMS1 and SMS...

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Detalles Bibliográficos
Autores principales: Guo, Yifan, Chang, Lin, Zhang, Ge, Gao, Zhanyan, Lin, Hao, Zhang, Yuting, Hu, Liang, Chen, She, Fan, Bing, Zhang, Si, Xue, Ruyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082820/
https://www.ncbi.nlm.nih.gov/pubmed/33910580
http://dx.doi.org/10.1186/s12959-021-00282-x