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Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process

BACKGROUND: Stem cells that have undergone long-term ex vivo expansion are most likely functionally compromised (namely cellular senescence) in terms of their stem cell properties and therapeutic potential. Due to its ability to attenuate cellular senescence, melatonin (MLT) has been proposed as an...

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Detalles Bibliográficos
Autores principales: Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yin, Yuan, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Tian, Bei-Min, Chen, Fa-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082824/
https://www.ncbi.nlm.nih.gov/pubmed/33926537
http://dx.doi.org/10.1186/s13287-021-02322-9