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Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
BACKGROUND: Stem cells that have undergone long-term ex vivo expansion are most likely functionally compromised (namely cellular senescence) in terms of their stem cell properties and therapeutic potential. Due to its ability to attenuate cellular senescence, melatonin (MLT) has been proposed as an...
Autores principales: | Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yin, Yuan, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Tian, Bei-Min, Chen, Fa-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082824/ https://www.ncbi.nlm.nih.gov/pubmed/33926537 http://dx.doi.org/10.1186/s13287-021-02322-9 |
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