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Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness

BACKGROUND: Glioblastoma is the most frequent and high-grade adult malignant central nervous system tumor. The prognosis is still poor despite the use of combined therapy involving maximal surgical resection, radiotherapy, and chemotherapy. Metabolic reprogramming currently is recognized as one of t...

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Detalles Bibliográficos
Autores principales: Moreira Franco, Yollanda E., Alves, Maria Jose, Uno, Miyuki, Moretti, Isabele Fattori, Trombetta-Lima, Marina, de Siqueira Santos, Suzana, dos Santos, Ancely Ferreira, Arini, Gabriel Santos, Baptista, Mauricio S., Lerario, Antonio Marcondes, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082835/
https://www.ncbi.nlm.nih.gov/pubmed/33910646
http://dx.doi.org/10.1186/s40170-021-00255-8