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Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness
BACKGROUND: Glioblastoma is the most frequent and high-grade adult malignant central nervous system tumor. The prognosis is still poor despite the use of combined therapy involving maximal surgical resection, radiotherapy, and chemotherapy. Metabolic reprogramming currently is recognized as one of t...
Autores principales: | Moreira Franco, Yollanda E., Alves, Maria Jose, Uno, Miyuki, Moretti, Isabele Fattori, Trombetta-Lima, Marina, de Siqueira Santos, Suzana, dos Santos, Ancely Ferreira, Arini, Gabriel Santos, Baptista, Mauricio S., Lerario, Antonio Marcondes, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082835/ https://www.ncbi.nlm.nih.gov/pubmed/33910646 http://dx.doi.org/10.1186/s40170-021-00255-8 |
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