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Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149

BACKGROUND: Hesperidin, a natural flavanone, has been proven to have multiple protective effects in diabetic rats, such as antioxidant, anti-inflammatory and anti-apoptotic effects. However, the molecular mechanisms underlying the effects of hesperidin are not well elucidated. METHODS: LO2 cells wer...

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Detalles Bibliográficos
Autores principales: Tian, Miao, Han, Yu-Bo, Zhao, Cheng-Cheng, Liu, Li, Zhang, Fu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082863/
https://www.ncbi.nlm.nih.gov/pubmed/33926520
http://dx.doi.org/10.1186/s13098-021-00664-1