Cargando…

Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149

BACKGROUND: Hesperidin, a natural flavanone, has been proven to have multiple protective effects in diabetic rats, such as antioxidant, anti-inflammatory and anti-apoptotic effects. However, the molecular mechanisms underlying the effects of hesperidin are not well elucidated. METHODS: LO2 cells wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Miao, Han, Yu-Bo, Zhao, Cheng-Cheng, Liu, Li, Zhang, Fu-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082863/ https://www.ncbi.nlm.nih.gov/pubmed/33926520 http://dx.doi.org/10.1186/s13098-021-00664-1

Ejemplares similares

β-elemene alleviates airway stenosis via the ILK/Akt pathway modulated by MIR143HG sponging miR-1275
por: Zhang, Guoying, et al.
Publicado: (2021)

Association of miR-146a, miR-149, miR-196a2, miR-499 gene polymorphisms with ischemic stroke in a Chinese people
por: Luo, Hong-Cheng, et al.
Publicado: (2017)

miR-149 in Human Cancer: A Systemic Review
por: He, Yunjie, et al.
Publicado: (2018)

Macrophage miR-149-5p induction is a key driver and therapeutic target for BRONJ
por: Shen, Xin, et al.
Publicado: (2022)

miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway
por: Zhu, Zhongsheng, et al.
Publicado: (2021)

Circulating miR-765 and miR-149: Potential Noninvasive Diagnostic Biomarkers for Geriatric Coronary Artery Disease Patients
por: Ali Sheikh, Md Sayed, et al.
Publicado: (2015)

Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations
por: Zhang, Xing, et al.
Publicado: (2015)

A Review on the Role of miR-149-5p in the Carcinogenesis
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

Anesthetic propofol epigenetically regulates breast cancer trastuzumab resistance through IL-6/miR-149-5p axis
por: Tian, Dan, et al.
Publicado: (2020)

Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway
por: Liang, Yu, et al.
Publicado: (2019)

Association study of miR‐149, miR‐196a2, and miR‐499a polymorphisms with coronary artery aneurysm of Kawasaki disease in southern Chinese population
por: Fu, Lanyan, et al.
Publicado: (2022)

miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastoma
por: Mao, Fengxia, et al.
Publicado: (2019)

The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression
por: Wu, Weining, et al.
Publicado: (2019)

The Association between Two MicroRNA Variants (miR-499, miR-149) and Gastrointestinal Cancer Risk: A Meta-Analysis
por: Li, Li, et al.
Publicado: (2013)

Hesperidin alleviates zinc oxide nanoparticle induced hepatotoxicity and oxidative stress
por: Ansar, Sabah, et al.
Publicado: (2018)

MiR-149-5p: An Important miRNA Regulated by Competing Endogenous RNAs in Diverse Human Cancers
por: Ren, Fu-jia, et al.
Publicado: (2021)

Restoring the Platelet miR-223 by Calpain Inhibition Alleviates the Neointimal Hyperplasia in Diabetes
por: Su, Meiling, et al.
Publicado: (2020)

Clinical Significance of miR-149 in the Survival of Patients with Laryngeal Squamous Cell Carcinoma
por: Xu, Yi, et al.
Publicado: (2016)

Association of MiR-149 (RS2292832) Variant with the Risk of Coronary Artery Disease
por: Ghaffarzadeh, Maryam, et al.
Publicado: (2017)

miR‐149 controls non‐alcoholic fatty liver by targeting FGF‐21
por: Xiao, Junjie, et al.
Publicado: (2016)

Effect of miR-149-5p on intramuscular fat deposition in pigs based on metabolomics and transcriptomics
por: Liu, Yingke, et al.
Publicado: (2023)

Hsa-miR-149-5p Suppresses Prostate Carcinoma Malignancy by Suppressing RGS17
por: Ma, Jinhua, et al.
Publicado: (2021)

miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1
por: Li, Dan, et al.
Publicado: (2021)

Associations of miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms with Ischemic Stroke in the Northern Chinese Han Population
por: Zhu, Xiaoyan, et al.
Publicado: (2018)

Association of miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms with Ossification of the Posterior Longitudinal Ligament of the Cervical Spine
por: Lim, Jae Joon, et al.
Publicado: (2016)

HOXA5-miR-574-5p axis promotes adipogenesis and alleviates insulin resistance
por: Li, Yuying, et al.
Publicado: (2021)

MiR‐149 sensitizes esophageal cancer cell lines to cisplatin by targeting DNA polymerase β
por: Wang, Yuanyuan, et al.
Publicado: (2018)

Dinitrosopiperazine‐decreased PKP3 through upregulating miR‐149 participates in nasopharyngeal carcinoma metastasis
por: Li, Yuejin, et al.
Publicado: (2018)

CircMMP9 accelerates the progression of hepatocellular carcinoma through the miR-149/CCND2 axis
por: Li, Xiaolou, et al.
Publicado: (2022)

miR-149-3p Regulates the Switch between Adipogenic and Osteogenic Differentiation of BMSCs by Targeting FTO
por: Li, Yuan, et al.
Publicado: (2019)

Metformin Alleviates Epirubicin-Induced Endothelial Impairment by Restoring Mitochondrial Homeostasis
por: Sun, Qi, et al.
Publicado: (2022)

Hesperidin Ameliorates Immobilization-Stress-Induced Behavioral and Biochemical Alterations and Mitochondrial Dysfunction in Mice by Modulating Nitrergic Pathway
por: Viswanatha, G. L., et al.
Publicado: (2012)

MiR-149 Aggravates Pyroptosis in Myocardial Ischemia-Reperfusion Damage via Silencing FoxO3
por: Lin, Jie, et al.
Publicado: (2019)

DNMT3A Regulates miR-149 DNA Methylation to Activate NOTCH1/Hedgehog Pathway to Promote the Development of Junctional Osteosarcoma
por: Cheng, Shigao, et al.
Publicado: (2022)

miR-497/MIR497HG inhibits glioma cell proliferation by targeting CCNE1 and the miR-588/TUSC1 axis
por: Ji, Li-Ya, et al.
Publicado: (2021)

Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice
por: Cheng, Chak-Kwong, et al.
Publicado: (2022)

Novel long noncoding RNA GACAT3 promotes colorectal cancer cell proliferation, invasion, and migration through miR-149
por: Zhou, Weiwei, et al.
Publicado: (2018)

Decay chain $^{149}_{64}$Gd --> $^{149}_{63}$Eu --> $^{149}_{62}$Sm
por: Cabrera, J A, et al.
Publicado: (1991)

Association of Tag SNPs and Rare CNVs of the MIR155HG/miR-155 Gene with Epilepsy in the Chinese Han Population
por: Tao, Hua, et al.
Publicado: (2015)

Hesperidin Alleviates Methotrexate-Induced Memory Deficits via Hippocampal Neurogenesis in Adult Rats
por: Naewla, Salinee, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4ijdegplo61kiojucee4o9lnp6