Whole-genome sequencing with long reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer

BACKGROUND: Identification of germline variation and somatic mutations is a major issue in human genetics. However, due to the limitations of DNA sequencing technologies and computational algorithms, our understanding of genetic variation and somatic mutations is far from complete. METHODS: In the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujimoto, Akihiro, Wong, Jing Hao, Yoshii, Yukiko, Akiyama, Shintaro, Tanaka, Azusa, Yagi, Hitomi, Shigemizu, Daichi, Nakagawa, Hidewaki, Mizokami, Masashi, Shimada, Mihoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082928/
https://www.ncbi.nlm.nih.gov/pubmed/33910608
http://dx.doi.org/10.1186/s13073-021-00883-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082928/
https://www.ncbi.nlm.nih.gov/pubmed/33910608
http://dx.doi.org/10.1186/s13073-021-00883-1

Ejemplares similares