HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8(+) T and NK cells: a novel therapeutic tumour vaccine

BACKGROUND: CD8(+) T cell-mediated adaptive cellular immunity and natural killer (NK) cell-mediated innate immunity both play important roles in tumour immunity. This study aimed to develop therapeutic tumour vaccines based on double-activation of CD8(+) T and NK cells. METHODS: The immune Epitope d...

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Detalles Bibliográficos
Autores principales: Yu, Zhaojin, Liu, Wensi, He, Ying, Sun, Mingli, Yu, Jiankun, Jiao, Xue, Han, Qiang, Tang, Haichao, Zhang, Bing, Xian, Yunkai, Qi, Jing, Gong, Jing, Xin, Wang, Shi, Gang, Shan, Fengping, Zhang, Rui, Li, Jianping, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082934/
https://www.ncbi.nlm.nih.gov/pubmed/33910591
http://dx.doi.org/10.1186/s13045-021-01081-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082934/
https://www.ncbi.nlm.nih.gov/pubmed/33910591
http://dx.doi.org/10.1186/s13045-021-01081-7

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