Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

PURPOSE: Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a key pathological event in proliferative retinal diseases such as proliferative vitreoretinopathy (PVR). This study aimed to explore a new method to reverse EMT in RPE cells to develop an improved therapy...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Wu, Binxin, He, Jian Feng, Chen, Jingyao, Kang, Zi Wei, Liu, Dandan, Luo, Junjie, Fang, Kexin, Leng, Xiaoxu, Tian, Haibin, Xu, Jingying, Jin, Caixia, Zhang, Jieping, Wang, Juan, Zhang, Jingfa, Ou, Qingjian, Lu, Lixia, Gao, Furong, Xu, Guo-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083104/
https://www.ncbi.nlm.nih.gov/pubmed/33861322
http://dx.doi.org/10.1167/iovs.62.4.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083104/
https://www.ncbi.nlm.nih.gov/pubmed/33861322
http://dx.doi.org/10.1167/iovs.62.4.21

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