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Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

Cyclodipeptide synthases (CDPSs) produce a variety of cyclic dipeptide products by utilising two aminoacylated tRNA substrates. We sought to investigate the minimal requirements for substrate usage in this class of enzymes as the relationship between CDPSs and their substrates remains elusive. Here,...

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Detalles Bibliográficos
Autores principales: Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084100/
https://www.ncbi.nlm.nih.gov/pubmed/33937777
http://dx.doi.org/10.1039/d0cb00142b