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Effect of O-linked glycosylation on the antigenicity, cellular uptake and trafficking in dendritic cells of recombinant Ber e 1

Ber e 1, a major Brazil nut allergen, has been successfully produced in the yeast Pichia pastoris expression system as homogenous recombinant Ber e 1 (rBer e 1) with similar physicochemical properties and identical immunoreactivity to its native counterpart, nBer e 1. However, O-linked glycans was d...

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Detalles Bibliográficos
Autores principales: Jambari, Nuzul N., Liddell, Susan, Martinez-Pomares, Luisa, Alcocer, Marcos J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084162/
https://www.ncbi.nlm.nih.gov/pubmed/33914740
http://dx.doi.org/10.1371/journal.pone.0249876