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Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen

Although current antiretroviral therapies (ART) are successful in controlling HIV-1 infection, a stable viral reservoir reactivates when ART is discontinued. Consequently, there is a major research effort to develop approaches to disrupt the latent viral reservoir and enhance the immune system’s abi...

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Detalles Bibliográficos
Autores principales: Liu, Hongbing, Hu, Pei-Wen, Dubrulle, Julien, Stossi, Fabio, Nikolai, Bryan C., Mancini, Michael A., Rice, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084242/
https://www.ncbi.nlm.nih.gov/pubmed/33914760
http://dx.doi.org/10.1371/journal.pone.0244771