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Peculiarities of the Presentation of the Encephalitogenic MBP Peptide by HLA-DR Complexes Providing Protection and Predisposition to Multiple Sclerosis

Predisposition to multiple sclerosis (MS), a chronic autoimmune disease of the central nervous system, is due to various factors. The genetic component is considered one of the most important factors. HLA class II genes contribute the most to the development of MS. The HLA-DRB1*15 allele group is co...

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Detalles Bibliográficos
Autores principales: Mamedov, A. E., Filimonova, I. N., Smirnov, I. V., Belogurov, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084299/
https://www.ncbi.nlm.nih.gov/pubmed/33959392
http://dx.doi.org/10.32607/actanaturae.11008