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Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions
The binding affinities of protein-nucleic acid interactions could be altered due to missense mutations occurring in DNA- or RNA-binding proteins, therefore resulting in various diseases. Unfortunately, a systematic comparison and prediction of the effects of mutations on protein-DNA and protein-RNA...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084330/ https://www.ncbi.nlm.nih.gov/pubmed/33872313 http://dx.doi.org/10.1371/journal.pcbi.1008951 |