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Balancing the influenza neuraminidase and hemagglutinin responses by exchanging the vaccine virus backbone
Virions are a common antigen source for many viral vaccines. One limitation to using virions is that the antigen abundance is determined by the content of each protein in the virus. This caveat especially applies to viral-based influenza vaccines where the low abundance of the neuraminidase (NA) sur...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084346/ https://www.ncbi.nlm.nih.gov/pubmed/33872324 http://dx.doi.org/10.1371/journal.ppat.1009171 |