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High mobility group box-1 in hypothalamic paraventricular nuclei attenuates sympathetic tone in rats at post-myocardial infarction

BACKGROUND: Inflammation is associated with increased sympathetic drive in cardiovascular diseases. The paraventricular nucleus (PVN) of the hypothalamus is a key regulator of sympathetic nerve activity at post-myocardial infarction (MI). High mobility group box-1 (HMGB1) exhibits inflammatory cytok...

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Detalles Bibliográficos
Autores principales: Li, Pang, Jie, Yin, YuGen, Shi, Yu, Wang, Yan, Suhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084387/
https://www.ncbi.nlm.nih.gov/pubmed/30338842
http://dx.doi.org/10.5603/CJ.a2018.0117