A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

Intracisternal A-particles (IAPs) are endogenous retroviruses (ERVs) responsible for most insertional mutations in the mouse. Full-length IAPs harbour genes flanked by long terminal repeats (LTRs). Here, we identify a solo LTR IAP variant (Iap5-1(solo)) recently formed in the inbred C57BL/6J mouse s...

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Detalles Bibliográficos
Autores principales: Bertozzi, Tessa M, Takahashi, Nozomi, Hanin, Geula, Kazachenka, Anastasiya, Ferguson-Smith, Anne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084528/
https://www.ncbi.nlm.nih.gov/pubmed/33755012
http://dx.doi.org/10.7554/eLife.65233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084528/
https://www.ncbi.nlm.nih.gov/pubmed/33755012
http://dx.doi.org/10.7554/eLife.65233

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