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Tumor-derived exosomal long noncoding RNA LINC01133, regulated by Periostin, contributes to pancreatic ductal adenocarcinoma epithelial-mesenchymal transition through the Wnt/β-catenin pathway by silencing AXIN2

Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies and rapidly progressive diseases. Exosomes and long noncoding RNAs (lncRNAs) are emerging as vital mediators in tumor cells and their microenvironment. However, the detailed roles and mechanisms of exosomal lncRNAs in PDAC...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Tang, Tianchi, Yang, Xiaosheng, Qin, Peng, Wang, Pusen, Zhang, Huiping, Bai, Min, Wu, Rong, Li, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084735/
https://www.ncbi.nlm.nih.gov/pubmed/33824474
http://dx.doi.org/10.1038/s41388-021-01762-0