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The Impact of Differentiation on Cytotoxicity and Insulin Sensitivity in Streptozotocin Treated SH-SY5Y Cells

Recently neuronal insulin resistance was suggested playing a role in Alzheimer’s disease. Streptozotocin (STZ) is commonly used to induce impairment in insulin metabolism. In our previous work on undifferentiated SH-SY5Y cells the compound exerted cytotoxicity without altering insulin sensitivity. N...

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Detalles Bibliográficos
Autores principales: Bagaméry, Fruzsina, Varga, Kamilla, Kecsmár, Kitti, Vincze, István, Szökő, Éva, Tábi, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084777/
https://www.ncbi.nlm.nih.gov/pubmed/33616807
http://dx.doi.org/10.1007/s11064-021-03269-2