Functional Elucidation of TfuA in Peptide Backbone Thioamidation

YcaO enzymes catalyze several post-translational modifications on peptide substrates, including thioamidation, which substitutes an amide oxygen with sulfur. The majority of predicted thioamide-forming YcaO enzymes are encoded adjacent to TfuA, which when present, is required for thioamidation. Whil...

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Detalles Bibliográficos
Autores principales: Liu, Andi, Si, Yuanyuan, Dong, Shi-Hui, Mahanta, Nilkamal, Penkala, Haley N., Nair, Satish K., Mitchell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084935/
https://www.ncbi.nlm.nih.gov/pubmed/33707784
http://dx.doi.org/10.1038/s41589-021-00771-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084935/
https://www.ncbi.nlm.nih.gov/pubmed/33707784
http://dx.doi.org/10.1038/s41589-021-00771-0

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