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HMGA1B/2 transcriptionally activated-POU1F1 facilitates gastric carcinoma metastasis via CXCL12/CXCR4 axis-mediated macrophage polarization

Tumor-associated macrophages (TAMs) in the tumor microenvironment contribute to poor prognosis in gastric cancer (GC). However, the underlying mechanism by which TAMs promote GC progression and metastasis remains elusive. Expression of POU1F1 was detected in 60 matched GC-normal tissue pairs using q...

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Detalles Bibliográficos
Autores principales: Tang, Cheng, Lei, Xiong, Xiong, Lingqiang, Hu, Zhigao, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084942/
https://www.ncbi.nlm.nih.gov/pubmed/33927188
http://dx.doi.org/10.1038/s41419-021-03703-x