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Inducible knockout of Clec16a in mice results in sensory neurodegeneration
CLEC16A has been shown to play a role in autophagy/mitophagy processes. Additionally, genetic variants in CLEC16A have been implicated in multiple autoimmune diseases. We generated an inducible whole-body knockout, Clec16a(ΔUBC) mice, to investigate the loss of function of CLEC16A. The mice exhibite...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084945/ https://www.ncbi.nlm.nih.gov/pubmed/33927318 http://dx.doi.org/10.1038/s41598-021-88895-0 |