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Slow viral propagation during initial phase of infection leads to viral persistence in mice

Immune evasion of pathogens can modify the course of infection and impact viral persistence and pathology. Here, using different strains of the lymphocytic choriomeningitis virus (LCMV) model system, we show that slower propagation results in limited type I interferon (IFN-I) production and viral pe...

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Detalles Bibliográficos
Autores principales: Xu, Haifeng C., Wang, Ruifeng, Shinde, Prashant V., Walotka, Lara, Huang, Anfei, Poschmann, Gereon, Huang, Jun, Liu, Wei, Stühler, Kai, Schaal, Heiner, Bergthaler, Andreas, Pandyra, Aleksandra A., Hardt, Cornelia, Lang, Karl S., Lang, Philipp A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084999/
https://www.ncbi.nlm.nih.gov/pubmed/33927339
http://dx.doi.org/10.1038/s42003-021-02028-x