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Slow viral propagation during initial phase of infection leads to viral persistence in mice
Immune evasion of pathogens can modify the course of infection and impact viral persistence and pathology. Here, using different strains of the lymphocytic choriomeningitis virus (LCMV) model system, we show that slower propagation results in limited type I interferon (IFN-I) production and viral pe...
Autores principales: | Xu, Haifeng C., Wang, Ruifeng, Shinde, Prashant V., Walotka, Lara, Huang, Anfei, Poschmann, Gereon, Huang, Jun, Liu, Wei, Stühler, Kai, Schaal, Heiner, Bergthaler, Andreas, Pandyra, Aleksandra A., Hardt, Cornelia, Lang, Karl S., Lang, Philipp A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084999/ https://www.ncbi.nlm.nih.gov/pubmed/33927339 http://dx.doi.org/10.1038/s42003-021-02028-x |
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