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Direct conversion of porcine primary fibroblasts into hepatocyte-like cells

The pig is an important model organism for biomedical research, mainly due to its extensive genetic, physiological and anatomical similarities with humans. Until date, direct conversion of somatic cells into hepatocyte-like cells (iHeps) has only been achieved in rodents and human cells. Here, we em...

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Detalles Bibliográficos
Autores principales: Fráguas-Eggenschwiler, Mariane, Eggenschwiler, Reto, Söllner, Jenny-Helena, Cortnumme, Leon, Vondran, Florian W. R., Cantz, Tobias, Ott, Michael, Niemann, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085017/
https://www.ncbi.nlm.nih.gov/pubmed/33927320
http://dx.doi.org/10.1038/s41598-021-88727-1