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Direct conversion of porcine primary fibroblasts into hepatocyte-like cells
The pig is an important model organism for biomedical research, mainly due to its extensive genetic, physiological and anatomical similarities with humans. Until date, direct conversion of somatic cells into hepatocyte-like cells (iHeps) has only been achieved in rodents and human cells. Here, we em...
Autores principales: | Fráguas-Eggenschwiler, Mariane, Eggenschwiler, Reto, Söllner, Jenny-Helena, Cortnumme, Leon, Vondran, Florian W. R., Cantz, Tobias, Ott, Michael, Niemann, Heiner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085017/ https://www.ncbi.nlm.nih.gov/pubmed/33927320 http://dx.doi.org/10.1038/s41598-021-88727-1 |
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