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NF-κB-Induced Upregulation of miR-146a-5p Promoted Hippocampal Neuronal Oxidative Stress and Pyroptosis via TIGAR in a Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a common neurodegenerative disorder that places a heavy burden on patients and society. Hippocampal neuronal loss is a hallmark of AD progression. Therefore, understanding the mechanism underlying hippocampal neuronal death would be of great importance for the diagnosis a...

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Detalles Bibliográficos
Autores principales: Lei, Bo, Liu, Jiaxin, Yao, Zhihui, Xiao, Yan, Zhang, Xiaoling, Zhang, Yueting, Xu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085266/
https://www.ncbi.nlm.nih.gov/pubmed/33935653
http://dx.doi.org/10.3389/fncel.2021.653881