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DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids
For nearly all eukaryotic cells, stochastic DNA double-strand breaks (DSBs) are one of the most deleterious types of DNA lesions. DSB processing and repair can cause sequence deletions, loss of heterozygosity, and chromosome rearrangements resulting in cell death or carcinogenesis. However, trypanos...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085331/ https://www.ncbi.nlm.nih.gov/pubmed/33937271 http://dx.doi.org/10.3389/fcell.2021.669041 |