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Inhibiting Pyridoxal Kinase of Entamoeba histolytica Is Lethal for This Pathogen
Pyridoxal 5’-phosphate (PLP) functions as a cofactor for hundreds of different enzymes that are crucial to the survival of microorganisms. PLP-dependent enzymes have been extensively characterized and proposed as drug targets in Entamoeba histolytica. This pathogen is unable to synthesize vitamin B(...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085340/ https://www.ncbi.nlm.nih.gov/pubmed/33937101 http://dx.doi.org/10.3389/fcimb.2021.660466 |