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Inhibiting Pyridoxal Kinase of Entamoeba histolytica Is Lethal for This Pathogen

Pyridoxal 5’-phosphate (PLP) functions as a cofactor for hundreds of different enzymes that are crucial to the survival of microorganisms. PLP-dependent enzymes have been extensively characterized and proposed as drug targets in Entamoeba histolytica. This pathogen is unable to synthesize vitamin B(...

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Detalles Bibliográficos
Autores principales:	Devi, Suneeta, Tomar, Priya, Faisal Tarique, Khaja, Gourinath, Samudrala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085340/ https://www.ncbi.nlm.nih.gov/pubmed/33937101 http://dx.doi.org/10.3389/fcimb.2021.660466

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