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Deletion of the ATP2 Gene in Candida albicans Blocks Its Escape From Macrophage Clearance

Macrophages provide the first-line defense against invasive fungal infections and, therefore, escape from macrophage becomes the basis for the establishment of Candida albicans invasive infection. Here, we found that deletion of ATP2 (atp2Δ/Δ) in C. albicans resulted in a dramatic decrease from 69.2...

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Detalles Bibliográficos
Autores principales: Zhang, Yishan, Tang, Chuanyan, Zhang, Zhanpeng, Li, Shuixiu, Zhao, Yajing, Weng, Luobei, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085345/
https://www.ncbi.nlm.nih.gov/pubmed/33937095
http://dx.doi.org/10.3389/fcimb.2021.643121