Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes

Beta-cell destruction in type 1 diabetes (T1D) results from the combined effect of inflammation and recurrent autoimmunity. In response to inflammatory signals, beta-cells engage adaptive mechanisms where the endoplasmic reticulum (ER) and mitochondria act in concert to restore cellular homeostasis....

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Detalles Bibliográficos
Autores principales: Vig, Saurabh, Lambooij, Joost M., Zaldumbide, Arnaud, Guigas, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085402/
https://www.ncbi.nlm.nih.gov/pubmed/33936111
http://dx.doi.org/10.3389/fimmu.2021.669492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085402/
https://www.ncbi.nlm.nih.gov/pubmed/33936111
http://dx.doi.org/10.3389/fimmu.2021.669492

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