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Secondary Nucleation and the Conservation of Structural Characteristics of Amyloid Fibril Strains

Amyloid fibrils are ordered protein aggregates and a hallmark of many severe neurodegenerative diseases. Amyloid fibrils form through primary nucleation from monomeric protein, grow through monomer addition and proliferate through fragmentation or through the nucleation of new fibrils on the surface...

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Detalles Bibliográficos
Autores principales: Hadi Alijanvand, Saeid, Peduzzo, Alessia, Buell, Alexander K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085410/
https://www.ncbi.nlm.nih.gov/pubmed/33937341
http://dx.doi.org/10.3389/fmolb.2021.669994