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Secondary Nucleation and the Conservation of Structural Characteristics of Amyloid Fibril Strains
Amyloid fibrils are ordered protein aggregates and a hallmark of many severe neurodegenerative diseases. Amyloid fibrils form through primary nucleation from monomeric protein, grow through monomer addition and proliferate through fragmentation or through the nucleation of new fibrils on the surface...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085410/ https://www.ncbi.nlm.nih.gov/pubmed/33937341 http://dx.doi.org/10.3389/fmolb.2021.669994 |