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USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors
Nucleotide excision repair (NER) is a pathway involved in the repair of a variety of potentially mutagenic lesions that distort the DNA double helix. The ubiquitin E3-ligase complex UV-DDB is required for the recognition and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) lesions through N...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085418/ https://www.ncbi.nlm.nih.gov/pubmed/33937266 http://dx.doi.org/10.3389/fcell.2021.663411 |