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LCT-3d Induces Oxidative Stress-Mediated Apoptosis by Upregulating Death Receptor 5 in Gastric Cancer Cells

Gastric cancer is a global health problem. In this study, we investigate the role of a novel Indole derivative, named LCT-3d, in inhibiting the growth of gastric cancer cells by MTT assay. The Western blotting results showed that LCT-3d modulated the mitochondrial-related proteins and Cleaved-Caspas...

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Detalles Bibliográficos
Autores principales: Wang, Menglin, Wu, Xinxin, Yu, Lu, Hu, Zi-yun, Li, Xiaobo, Meng, Xia, Lv, Chun-tao, Kim, Gi-Young, Choi, Yung Hyun, Wang, Zhengya, Xu, Hai-Wei, Jin, Cheng-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085419/
https://www.ncbi.nlm.nih.gov/pubmed/33937072
http://dx.doi.org/10.3389/fonc.2021.658608