Cargando…

LCT-3d Induces Oxidative Stress-Mediated Apoptosis by Upregulating Death Receptor 5 in Gastric Cancer Cells

Gastric cancer is a global health problem. In this study, we investigate the role of a novel Indole derivative, named LCT-3d, in inhibiting the growth of gastric cancer cells by MTT assay. The Western blotting results showed that LCT-3d modulated the mitochondrial-related proteins and Cleaved-Caspas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Menglin, Wu, Xinxin, Yu, Lu, Hu, Zi-yun, Li, Xiaobo, Meng, Xia, Lv, Chun-tao, Kim, Gi-Young, Choi, Yung Hyun, Wang, Zhengya, Xu, Hai-Wei, Jin, Cheng-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085419/ https://www.ncbi.nlm.nih.gov/pubmed/33937072 http://dx.doi.org/10.3389/fonc.2021.658608

Ejemplares similares

NDUFC1 Is Upregulated in Gastric Cancer and Regulates Cell Proliferation, Apoptosis, Cycle and Migration
por: Xu, Liang, et al.
Publicado: (2021)

Comparative genomic analysis of Klebsiella pneumonia (LCT-KP214) and a mutant strain (LCT-KP289) obtained after spaceflight
por: Guo, Yinghua, et al.
Publicado: (2014)

Association of LCT-13910 C/T Polymorphism and Colorectal Cancer
por: Gençdal, Genco, et al.
Publicado: (2017)

The origin of gastric cancer stem cells and their effects on gastric cancer: Novel therapeutic targets for gastric cancer
por: Yang, Ying, et al.
Publicado: (2022)

Draft Genome Sequence of Escherichia coli Strain LCT-EC59
por: Li, Tianzhi, et al.
Publicado: (2013)

Draft Genome Sequences of the Enterococcus faecium Strain LCT-EF258
por: Chang, De, et al.
Publicado: (2013)

Sustained Exposure to Helicobacter pylori Lysate Inhibits Apoptosis and Autophagy of Gastric Epithelial Cells
por: He, Yang, et al.
Publicado: (2020)

Draft Genome Sequences and Annotation of Enterococcus faecium Strain LCT-EF20
por: Chang, De, et al.
Publicado: (2013)

LCT‐22018G>A single nucleotide polymorphism is a better predictor of adult‐type hypolactasia/lactase persistence in Japanese‐Brazilians than LCT‐13910C>T
por: Mattar, Rejane, et al.
Publicado: (2010)

Clinical Utility of LCT Genotyping in Children with Suspected Functional Gastrointestinal Disorder
por: Couce, María L., et al.
Publicado: (2020)

Immediate Response to Brentuximab Vedotin in a Patient with Localized MF-LCT
por: Giza, Agnieszka, et al.
Publicado: (2023)

Cancer Stem Cells and the Tumor Microenvironment in Gastric Cancer
por: Yang, Ying, et al.
Publicado: (2022)

Genomic characterization of Escherichia coli LCT-EC001, an extremely multidrug-resistant strain with an amazing number of resistance genes
por: Zhang, Xuelin, et al.
Publicado: (2019)

Dasatinib promotes TRAIL‐mediated apoptosis by upregulating CHOP‐dependent death receptor 5 in gastric cancer
por: Wang, Xiaona, et al.
Publicado: (2018)

Downregulation of hsa_circ_0001836 Induces Pyroptosis Cell Death in Glioma Cells via Epigenetically Upregulating NLRP1
por: Liu, Yong, et al.
Publicado: (2021)

Analysis of LCT-13910 genotypes and bone mineral density in ancient skeletal materials
por: Mnich, Barbara, et al.
Publicado: (2018)

Oridonin Sensitizes Cisplatin-Induced Apoptosis via AMPK/Akt/mTOR-Dependent Autophagosome Accumulation in A549 Cells
por: Yang, Huahong, et al.
Publicado: (2019)

Draft Genome Sequence of Bacillus cereus LCT-BC25, Isolated from Space Flight
por: Zhang, Xuelin, et al.
Publicado: (2014)

Clinical Value and Underlying Mechanisms of Upregulated LINC00485 in Hepatocellular Carcinoma
por: Zhu, Xinyu, et al.
Publicado: (2021)

Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways
por: Liu, Xihong, et al.
Publicado: (2019)

Genome Sequence of Bacillus cereus Strain LCT-BC235, Carried by the Shenzhou VIII Spacecraft
por: Su, Longxiang, et al.
Publicado: (2014)

Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway
por: Zhu, Li-Min, et al.
Publicado: (2021)

5-FU-Induced Upregulation of Exosomal PD-L1 Causes Immunosuppression in Advanced Gastric Cancer Patients
por: Zhang, Min, et al.
Publicado: (2020)

Expression of Human Epidermal Growth Factor Receptor-2 Status and Programmed Cell Death Protein-1 Ligand Is Associated With Prognosis in Gastric Cancer
por: Lv, Huifang, et al.
Publicado: (2021)

Four novel mutations in the lactase gene (LCT) underlying congenital lactase deficiency (CLD)
por: Torniainen, Suvi, et al.
Publicado: (2009)

Correction:Analysis of LCT-13910 genotypes and bone mineral density in ancient skeletal materials
por: Mnich, Barbara, et al.
Publicado: (2020)

Corrigendum: Expression of Human Epidermal Growth Factor Receptor-2 Status and Programmed Cell Death Protein-1 Ligand Is Associated With Prognosis in Gastric Cancer
por: Lv, Huifang, et al.
Publicado: (2021)

Genome Sequence of Enterococcus faecium Strain LCT-EF297, Which Has Specific Biochemical Features
por: An, Li, et al.
Publicado: (2014)

Genome Sequence of Pseudomonas aeruginosa Strain LCT-PA41, with Changed Metabolism after Space Flight
por: Liu, Chao, et al.
Publicado: (2014)

G6PD-NF-κB-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2
por: Chen, Bin, et al.
Publicado: (2021)

Rictor Activates Cav 1 Through the Akt Signaling Pathway to Inhibit the Apoptosis of Gastric Cancer Cells
por: Cao, Rui-zhen, et al.
Publicado: (2021)

Association of the European Lactase Persistence Variant (LCT-13910 C>T Polymorphism) with Obesity in the Canary Islands
por: Almon, Ricardo, et al.
Publicado: (2012)

Lipofundin MCT/LCT Inhibits Levcromakalim-Induced Vasodilation by Inhibiting Endothelial Nitric Oxide Release
por: Lee, Soo Hee, et al.
Publicado: (2020)

MCT/LCT Mixed Oil Phase Enhances the Rheological Property and Freeze-Thawing Stability of Emulsion
por: Liu, Jiahao, et al.
Publicado: (2022)

A Nomogram for Predicting Risk of Thromboembolism in Gastric Cancer Patients Receiving Chemotherapy
por: Yuan, Hai-Liang, et al.
Publicado: (2021)

Upregulation of miR-216a-5p by Lentinan Targeted Inhibition of JAK2/STAT3 Signaling Pathway to Reduce Lung Adenocarcinoma Cell Stemness, Promote Apoptosis, and Slow Down the Lung Adenocarcinoma Mechanisms
por: Chen, Quan, et al.
Publicado: (2021)

Penicilazaphilone C, a New Azaphilone, Induces Apoptosis in Gastric Cancer by Blocking the Notch Signaling Pathway
por: Wang, Ming, et al.
Publicado: (2020)

Positive Phospho-Focal Adhesion Kinase in Gastric Cancer Associates With Poor Prognosis After Curative Resection
por: Peng, Ke, et al.
Publicado: (2022)

Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells
por: Fang, Xing, et al.
Publicado: (2020)

The Role of Lipid Metabolism in Gastric Cancer
por: Cui, Meng-Ying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_drucdcdtafk5747km109ab0qdu