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Cytotoxic CD8+ T cells and tissue resident memory cells in colorectal cancer based on microsatellite instability and BRAF status

BACKGROUND: Recent studies in non-colorectal malignancy have associated T resident memory (T(RM)) cells with improved patient survival. It is unknown if T(RM) plays a role in colorectal cancer (CRC). AIM: To examine the potential role of T(RM) cells in providing immunogenicity in CRC stratified by m...

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Detalles Bibliográficos
Autores principales: Toh, James Wei Tatt, Ferguson, Angela L, Spring, Kevin J, Mahajan, Hema, Palendira, Umaimainthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085513/
https://www.ncbi.nlm.nih.gov/pubmed/33959477
http://dx.doi.org/10.5306/wjco.v12.i4.238