Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH

BACKGROUND: Mitochondrial uncouplers shuttle protons across the inner mitochondrial membrane via a pathway that is independent of adenosine triphosphate (ATP) synthase, thereby uncoupling nutrient oxidation from ATP production and dissipating the proton gradient as heat. While initial toxicity conce...

Descripción completa

Detalles Bibliográficos
Autores principales: Goedeke, Leigh, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085597/
https://www.ncbi.nlm.nih.gov/pubmed/33545391
http://dx.doi.org/10.1016/j.molmet.2021.101178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085597/
https://www.ncbi.nlm.nih.gov/pubmed/33545391
http://dx.doi.org/10.1016/j.molmet.2021.101178

Ejemplares similares