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Implantable blood clot loaded with BMP-2 for regulation of osteoimmunology and enhancement of bone repair

The treatment of large-area bone defects still faces many difficulties and challenges. Here, we developed a blood clot delivery platform loaded with BMP-2 protein (BMP-2@BC) for enhanced bone regeneration. Blood clot gel platform as natural biomaterials can be engineered from autologous blood. Once...

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Detalles Bibliográficos
Autores principales: Fan, Qin, Bai, Jinyu, Shan, Huajian, Fei, Ziying, Chen, Hao, Xu, Jialu, Ma, Qingle, Zhou, Xiaozhong, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085758/
https://www.ncbi.nlm.nih.gov/pubmed/33997490
http://dx.doi.org/10.1016/j.bioactmat.2021.04.008